The funniest paradox of the 21st century? Humans are increasing their lifespan, but experiencing a decline in health span at the same time.
We are living longer than ever, but our quality of life is being compromised by the rise of non-communicable diseases (NCDs). Chronic conditions like type 2 diabetes, cardiovascular diseases, and various cancers are becoming major health challenges.
This disconnect between lifespan and health span should push us to focus on enhancing the quality of those extra years. This includes better public health initiatives, lifestyle changes, and innovations in nutrition and medicine.
One promising development is Reducose®, a functional food ingredient from White Mulberry leaves.
Multiple clinical studies have shown that Reducose® helps manage blood sugar levels by converting fast sugars into slow ones, preventing constant blood sugar spikes—the root cause of many age-related diseases.
Learn how Reducose® can enhance your longevity. Because that’s what Avea is all about.
In this article
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What is Reducose®?
Reducose® is a patented White Mulberry leaf extract rich in alkaloids and flavonoids. Throughout this article, we’ll use both names to remind you that it’s 100% natural, so don’t get confused.
Alkaloids are naturally occurring compounds found in plants, known for their medicinal properties. They can help regulate blood sugar levels and improve insulin sensitivity, making them beneficial for preventing or managing diabetes as well as other metabolic disorders, including obesity.
Flavonoids are plant-based antioxidants that help protect your body against oxidative stress. They have anti-inflammatory properties, and can improve cardiovascular health by reducing the risk of atherosclerosis and other heart-related conditions.
Whilst they have recently gained popularity as ‘’superfoods’’ in the west, Mulberry leaves have been used in traditional medicine for ages in Asian countries for their blood sugar balancing benefits.
Where is Reducose® found in nature?
The Mulberry (Morus) tree is native to China. It belongs to the Moraceae plant family and includes several species.
Reducose® is extracted from White Mulberry leaves that are usually cultivated in West China, according to EU organic guidelines to achieve peak quality and sustainability.
These guidelines aim to produce high-quality leaves rich in beneficial compounds without the use of harmful chemicals, promoting both environmental health and consumer well-being.
How does Reducose® work?
It works by inhibiting the enzymes responsible for digesting carbohydrates.
Its mechanism of action is essentially, mimicking the effects of diets rich in fibre and resistant starch, leading to lower blood glucose and insulin responses, because the glucose in the carbohydrates isn’t available for absorption.
In short, your post-meal blood sugar levels are balanced without resulting into harmful spikes.
Reducose® inhibits these enzymes right at the start of digestion in your upper small intestine (duodenum) for about an hour.
This gives most ingested carbohydrates enough time to pass through your duodenum and part-way through your jejunum undigested, where monosaccharide digestion normally happens.
After about an hour, Reducose® dissociates from the digestive enzymes.
Unlike other ‘carb blockers’, it is absorbed out of your gut into your bloodstream and rapidly excreted unmetabolised through your kidneys.
This is crucial as it avoids disrupting your microbiome, which relies on the same enzymes to break down undigested foods. Since Reducose® exits your gut, it doesn’t interfere with this process.
The direct effect of Reducose® is to lower post-meal blood glucose by preventing carbohydrate digestion, triggering a cascade of positive health effects similar to those seen with low GI diets.
These benefits arise from the presence of undigested carbohydrates in the small intestine, not from any biological or biochemical effects of Reducose® itself.
Real-time control: Lower glucose spikes by 40%
- 500 mg of Reducose®, 500mg Berberine, and 200μg Chromium Picolinate.
- Stay energised throughout the day.
- Improve your metabolic health.
- Support healthy weight management.
What are the health benefits of using White Mulberry leaf extracts?
Reducose® does more than just regulate blood sugar levels; it also supports overall well-being, promoting longevity in several ways.
- Reduces post-meal blood glucose levels: Clinical trials have shown significant decreases in post-meal blood glucose levels with the use of Reducose®.
- Lowers insulin response: Reducose® significantly lowers insulin response after consuming carbohydrates, reducing the risks of developping insulin resistance.
- Enhances cognitive function: Lower insulin levels can improve memory, attention, and overall cognitive performance.
- No reported side effects: Reducose® has a strong safety profile, with no reported side effects.
- Unaltered and easily excreted: It remains unchanged in the body and is easily excreted.
- Acts as a prebiotic: The undigested carbohydrates act as prebiotics, feeding beneficial bacteria in the gut microbiome.
- Mimics calorie restriction: Reducose® mimics the effects of calorie restriction by preventing the absorption of some carbohydrates.
- Promotes satiety: It triggers satiety signals, helping you feel fuller faster and for longer periods, aiding in appetite control.
- Reduces snacking and cravings: Improved appetite control helps prevent excessive snacking and reduces cravings between meals.
- Supports digestive health: Promotes a healthy gut environment, contributing to improved digestive health and overall wellness.
Why do we use White Mulberry leaf extracts in our supplements?
We chose Reducose® as one of the key players in our Stabiliser, primarily for its ability to effectively reduce post-meal glucose spikes – a benchmark well-known for a healthy heart, healthy weight, and healthy ageing.
This effect can also be attained through challenging methods like calorie restriction or intermittent fasting, Reducose® just makes it easier, by allowing you to keep the foods you love.
Reducose® also supports cellular and DNA repair by inducing its anti-inflammatory and antioxidant effects. It frees up NAD+, a crucial molecule needed to activate the infamous ‘’longevity-genes’’ called sirtuins.
Researchers have firmly established sirtuins’ critical role as a longevity regulator, as they maintain healthy circadian rhythms and metabolism.
Another factor triggering our choice for Reducose® is that its immediate blood-glucose effect can be easily monitored in real-time via technological innovations like Continuous Glucose Monitor (CGM) which enables you to understand your metabolism.
CGMs not only help track efficacy of our supplement, but also play a crucial role in educating consumers about the surprising blood sugar effects of seemingly healthy foods.
Our uniqueness also stems from the additional benefits brought in by Berberine and Chromium Picolinate, included in our Stabiliser alongside Reducose®.
As a whole, the 3 chosen ingredients work in synergy to safely boost your body into a fat-burning mode, further helping you maintain a healthy blood-sugar level.
Whilst Berberine will act by lowering your fasting glucose levels, Reducose® will act on your post-meal glucose levels.
To top it off, Chromium will assist by considerably increasing your insulin activity. Our Stabiliser is the ultimate key to a healthy heart and a healthy weight!
Avea’s Stabiliser
| Immediate results: Experience the effects right away. Hidden sugars and carbs: Worry less about their impact. Feel balanced: Enjoy a better sense of well-being. Natural fit: Integrates easily into your daily routine. Love your food: Take back control and savour your meals again. |
The science behind Reducose®
1. Reducose® and its immediate impact on blood glucose
Backed by 9 human trials (more underway), Reducose® offers an effective solution for balancing blood glucose levels [1].
By preventing the digestion of carbohydrates, Reducose® transforms fast sugars into slower ones, reducing the amount of glucose entering your bloodstream. This process helps prevent high blood sugar spikes and crashes.
Reducose® inhibits alpha-glucosidase enzymes in the upper small intestine. These enzymes typically break down carbohydrates into glucose.
By keeping these enzymes occupied for about an hour, Reducose® addresses the root cause of high blood sugar. As a result, it significantly lowers post-meal blood sugar and insulin responses by 40%.
2. Reducose® and gut health
Reducose® stands out from other carb-blocking ingredients due to its unique absorption and excretion process.
After about an hour, Reducose® is absorbed through the gut wall into the bloodstream and then excreted unchanged via the kidneys in the urine.
This means it is inert inside your body and does not travel to the colon, thus avoiding disruptions to the microbiome and preventing the gastrointestinal side effects commonly seen with other carb blockers.
Balanced blood sugar levels also offer a bonus known as the “second-meal effect.” A lower blood sugar response to one meal helps your body maintain a lower blood sugar response to the next meal.
3. Reducose® and insulin
Reducose® helps prevent the absorption of glucose calories, significantly lowering the insulin response after consuming carbohydrates [2].
Insulin’s primary role is to help your cells remove glucose from your blood, maintaining glucose balance. Glucose is a vital energy source, and any excess is stored as glycogen and later as fat, with insulin facilitating this storage process.
High glycaemic index (GI) foods cause sharp spikes in blood glucose, leading to excess insulin production. This surplus insulin promotes fat storage, as calories that would normally be used for immediate energy are stored as fat.
Studies show that low GI meals not only reduce the glycaemic response but also improve appetite control and enhance fat oxidation.
By converting high GI foods into low GI ones, Reducose® puts your body into fat-burning mode. It may also stimulate the ileal brake, increasing satiety, and triggering the second meal effect, further supporting healthy weight loss.
4. Reducose® and weight loss
Reducose® works at cellular level to promote a healthy body weight and composition.
Clinical trials have demonstrated that it significantly lowers the insulin response after carbohydrate consumption and reduces the glycaemic index of foods [3].
This promotes fat burning and reduces the storage of glucose as fat. It also enhances insulin and leptin sensitivity due to its active compound, DNJ, helping in breaking the cycle of weight gain.
For those aiming to lose weight, Reducose® offers additional benefits by blocking a portion of carbohydrate calories from being absorbed.
These undigested carbs reach the distal small intestine, triggering the ileal brake—a mechanism that induces satiety by slowing gut motility, reducing appetite, and delaying gastric emptying through the release of hormones like PYY, CCK, and GLP-1.
The second-meal effect, linked to the ileal brake, occurs when the glycaemic index of one meal influences the glycaemic response to the next meal.
This effect benefits weight management by increasing fat oxidation and promoting fat use for energy, while high-GI meals favour fat storage and carbohydrate use for energy.
In a nutshell, Reducose® supports weight management in the following ways:
- Lowers hyperinsulinemia: Encourages calorie metabolism over storage.
- Prevents sugar crashes: Reduces hunger during the postprandial period.
- Enhances insulin and leptin sensitivity: Helps break the cycle of weight gain.
- Increases satiety: Activates the ileal brake to help manage hunger between meals, especially on a calorie-restricted diet.
- Stimulates the second-meal effect: Promotes healthy body composition through increased fat oxidation.
Stabilise your glucose levels with expert advice
- Learn how to reduce blood sugar spikes.
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Keynote from Avea
Reducose® is a patented functional food ingredient derived from a water extract of White Mulberry leaves, known for its ability to transform fast sugars into slow ones.
It can be seamlessly incorporated into various foods, drinks, or dietary supplements.
Avea’s Stabiliser combines Reducose® with Chromium and Berberine, creating a powerful formula to regulate blood sugar levels by slowing and blocking carb absorption during meals.
This minimises glucose peaks and prevents the “sugar crashes” that make you feel tired, all while letting you enjoy the foods you love.
The Stabiliser also enhances insulin sensitivity, helping you maintain a healthy weight and reduce the risk of metabolic diseases that become more common with age.
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