In the realm of natural health, few substances bridge the gap between ancient remedies and cutting-edge medical research as elegantly as Berberine.
This vibrant yellow compound, derived from the bark, roots, and rhizomes of various plants, has been a cornerstone in traditional medicine for over two millennia.
Today, it captivates the scientific world, not just for its historical significance, but for its proven potential in contemporary health interventions.
Join us as we delve into the science behind Berberine, understanding why it deserves a place in your daily wellness routine.
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What is Berberine?
Berberine is a bioactive compound classified as a polyphenol.
Polyphenols are produced as a defence mechanism against attack from fungi, bacteria, or insects.
They are essential for plant diversity, accounting for their flavour, colour, bitterness, and nutritional properties of plant-based foods.
Historically used for over 2500 years in Ayurvedic and Chinese medicine to treat myriad ailments, modern science has begun to unveil the mechanisms behind its remarkable therapeutic effects.
This can be evidenced by the 630+ papers published on Berberine in PubMed, in 2020 alone.
Berberine sources in nature
Many plant species contain Berberine including goldthread, Oregon grape, and barberry. Plants of this genus are often used against inflammation, infectious diseases, diabetes, constipation, and other pathologies.
These plants have not only survived, but thrived across different continents, from the Himalayas to North America, carrying with them a legacy of healing and health maintenance.
Whilst multiple studies revealed the beneficial effects of supplemental Berberine and barberry extracts, the relative amount of fresh or dried barberries to be consumed remains unclear.
How does Berberine work in the body?
Berberine stands out for its ability to activate AMP-activated protein kinase (AMPK), an enzyme often referred to as the ‘metabolic master switch’ [1]. AMPK plays a crucial role in regulating energy balance at both the cellular and whole-body levels.
When activated by Berberine, AMPK enhances glucose uptake and fat breakdown, whilst reducing the production of glucose in the liver.
This activation mirrors the beneficial effects typically associated with physical exercise and caloric restriction, making Berberine a potent tool for metabolic health.
Its health benefits have been extensively studied in clinical trials for lowering blood sugar, lipids, high cholesterol and hypertension.
No significant difference has been observed between the effects of Berberine and other Type II diabetes prescription drugs like metformin. In fact, both studies show similar declines in HbA1c levels (a marker of glucose management in diabetics), with no remarkable side effects from Berberine.
So let’s find out the health benefits of supplementing with Berberine.
Turns out, it will not only improve your blood-sugar levels, but also enhance your immune system and promote healthy brain cell production.
Health benefits of Berberine
1. Metabolic health
One of the most significant impacts of Berberine is on metabolic health, particularly its ability to improve insulin resistance and manage blood sugar levels.
Studies have consistently shown that Berberine can reduce blood glucose levels to a degree comparable to that of conventional diabetes medications like metformin.
By enhancing insulin sensitivity, Berberine not only helps control blood sugar levels, but also contributes to overall metabolic syndrome improvements [2].
This makes it a valuable option for not only those managing Type 2 diabetes or pre-diabetes, but also any smart fellow out there trying to increase his or her longevity.
2. Cognitive and immune benefits
Beyond its metabolic benefits, Berberine also exerts protective effects on brain health and immune system function.
Research indicates that Berberine can enhance cognitive functions, potentially through its anti-inflammatory properties and ability to reduce oxidative stress.
These actions are beneficial in slowing cognitive decline and may offer protective mechanisms against neurodegenerative diseases.
Additionally, its immune-enhancing properties help fortify your body’s defences against various pathogens and diseases.
3. Cardiovascular protection
Berberine’s benefits extend to cardiovascular health as well. It has been found to improve cholesterol levels by increasing the removal of LDL (bad) cholesterol from the bloodstream and reducing triglyceride levels.
It can also aid in lowering blood pressure, further reducing the risk of heart disease and stroke. These cardiovascular benefits are particularly important for those with metabolic conditions, as they often face higher risks of heart-related issues.
The Avea Stabiliser
Keeping these 3 powerful benefits of Berberine in mind, Avea developed the Stabiliser – a natural formula designed to enhance its effects.
Stabiliser helps reduce carbohydrate absorption by up to 40%, allowing you to maintain balanced blood sugar levels without experiencing significant spikes or crashes.
This means you can still enjoy your favourite foods while keeping your blood sugar in check.
Real-time control: Lower glucose spikes by 40%
- Stay energised throughout the day.
- Improve your metabolic health.
- Support healthy weight management.
Why is the Stabiliser the best Berberine supplement?
Our uniqueness also stems from the additional benefits brought in by Reducose® (White Mulberry leaf extract) and Chromium Picolinate, included in our Stabiliser alongside Berberine.
As a whole, the 3 chosen ingredients work in synergy to safely boost your body into a fat-burning mode, further helping you maintain a healthy blood-sugar level.
For instance, whilst Berberine will act by lowering your fasting glucose levels, Reducose® will act on your post-meal glucose levels.
To top it off, Chromium will assist by considerably increasing your insulin activity. Our stabiliser is the ultimate key to a healthy heart and a healthy weight!
What is Berberine supplement used for?
Berberine supplement can be used to reap benefits of its potential to activate the crucial enzyme AMPK, which essentially generates similar benefits to exercising, dieting or weight management—the healthy lifestyle modifications you know you should implement when it comes to improving your health, but which can sometimes still be challenging.
When used in combination with other nutrients, Berberine has consistently exhibited multiple pharmacological and therapeutic actions [3], such as:
- antioxidant properties
- immunomodulatory effects
- protective action on the cardiovascular system, liver and kidney
- endothelial relaxation
- regulating glucose metabolism
This is yet another major reason why we chose Berberine to partner with the other two ingredients in our Stabiliser supplement.
Customer reviews
Many of our customers have experienced first-hand the transformative effects of Stabiliser.
Many report feeling more energetic and less prone to the highs and lows of blood sugar fluctuations, which are often associated with mood swings and energy dips.
What dosage of Berberine should I take?
Adults are typically recommended to take Berberine in doses ranging from 0.4 to 1.5 g per day.
It’s also available in eye drops and gels. To determine the right product and dosage for your needs, it’s always a good idea to consult with a healthcare professional.
The safety of our customers is paramount, which is why Stabiliser contains a carefully calibrated dose of 500mg of Berberine per serving. This amount is designed to maximise benefits without causing discomfort or interacting with medications.
Side effects of Berberine
Although Berberine is generally considered safe, more research is needed to fully understand its long-term effects, especially for high dosages.
Some people may experience gastrointestinal side effects, such as diarrhoea, constipation, flatulence, or stomach pain, especially when taking doses above 500mg per day.
Given its ability to lower blood sugar, higher doses of Berberine could also increase the risk of hypoglycaemia.
Berberine can also inhibit certain enzymes responsible for drug metabolism, so it’s important to be mindful of potential interactions if you’re taking other medications or supplements.
Based on the latest research, our formula delivers an optimal amount of Berberine to support healthy blood sugar levels, whilst maintaining safety.
By following the recommended intake on our packaging, users can confidently incorporate the Stabiliser into their daily routine, knowing they are using a scientifically backed, safe, and effective product.
A keynote from Avea
From ancient forests where traditional healers harnessed its power, to modern labs validating its potent health benefits, Berberine is a perfect example of how historical wisdom meets cutting-edge science.
As we’ve seen, Berberine’s multifaceted benefits—ranging from metabolic health to cognitive and cardiovascular support—make it an essential ingredient in our Stabiliser supplement. It’s a natural, science-backed solution for those looking to optimise their health.
Join our community of wellness enthusiasts embracing nature’s time-tested remedies for a healthier, more vibrant life.
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