GLP-1 agonists alternatives you should know about

GLP-1 drugs like Ozempic have become the go-to for weight loss and blood sugar control—but at what cost?

Over €1000 per month, invasive injections, unpleasant side effects like nausea and fatigue, and shortages for those who truly need them—GLP-1 agonists are still far from being a solution for everyone.

What if you could achieve the same life-changing benefits without those downsides? Natural ingredients used since millennia, and clinically proven to:

• regulate blood sugar levels
• reduce cravings
• promote weight loss
• boost metabolic health

The science is clear. Similar mechanisms can be achieved with a more sustainable approach, and that’s where health-conscious folks are now focusing on: GLP-1 agonist alternatives.

Now, before you go fill up your kitchen counter with supplements that might not deliver on their promises, let’s dive into the science behind GLP-1 agonists.

Discover how GLP-1 agonists work, and what makes certain natural ingredients worth exploring for sustainable weight management and metabolic health.

Real-time control: Lower glucose spikes by 40%

• Reduced cravings
• Increased energy levels
• Weight management support
• Improved blood sugar levels

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Avea Stabiliser

What are GLP-1 agonists, and how do they work?

The role of GLP-1 in your body

To understand GLP-1 agonists, it’s essential to first look at GLP-1 itself. This hormone, naturally produced by specialised cells in your intestines, plays a key role in managing blood sugar levels.

Here’s how it works:

• Insulin stimulation: When blood sugar levels rise after eating, GLP-1 signals your pancreas to release insulin, the hormone responsible for converting glucose into energy.
• Reduced glucagon levels: It curbs the release of glucagon, another hormone that triggers the liver to release stored glucose, helping to keep blood sugar levels stable.
• Slows digestion: GLP-1 slows down the speed at which food leaves your stomach, preventing rapid spikes in blood sugar and helping you feel full longer.
• Boosts satiety: It communicates with your brain to suppress appetite, making you feel satisfied after meals.

However, in people with Type 2 diabetes, this process doesn’t work as it should. The GLP-1 hormone is quickly broken down by an enzyme called DPP-4, reducing its ability to regulate blood sugar effectively.

Scientists developed GLP-1 agonists to counteract this effect, and many of them are approved by the FDA to help treat diabetes, and some even obesity. 

How do GLP-1 agonists work?

An agonist is a drug or substance that attaches to a receptor, either inside a cell or on its surface, and mimics the action of the natural substance that typically binds to that receptor. GLP-1 agonists are medications designed to mimic the effects of the GLP-1 hormone[1]. 

By binding to the same receptors as the natural hormone, they stimulate insulin production, lower glucagon levels, slow digestion, and promote satiety—all vital for managing blood sugar and supporting weight loss.

The benefits of GLP-1 agonists

GLP-1 agonists have shown a range of health benefits:

• Improved blood sugar control
• Delayed gastric emptying and inhibiting glucagon production.
• Can promote an average weight loss of 2.9kg compared to placebo
• Cardiovascular benefits, including lower blood pressure and cholesterol
• Enhanced glucose uptakes in the muscles
• Neuroprotection
• Increased satiety 

The limitations of GLP-1 agonists

Whilst GLP-1 agonists offer impressive benefits, they also come with several significant drawbacks:

• They’re expensive, often costing over €1000 per month.
• Injections are invasive and inconvenient, requiring daily or weekly treatments, due to poor oral bioavailability.
• Side effects can range from nausea, vomiting, and diarrhoea to more serious issues like gallbladder problems.
• They’re not a cure for diabetes and don’t address the root causes of metabolic imbalances.
• Stopping them often leads to weight regain if lifestyle changes haven’t been made.
• There’s a rising shortage, leaving diabetics in need of these medications without access—an unfair and troubling situation.

Ozempic alternatives

Whilst Ozempic is the most well-known GLP-1 drug, it’s not the only option. Here’s a list of other Ozempic alternatives currently on the market. 

However, since all these GLP-1 agonists all work in similar ways, the side effects and high pricing remain consistent across the board.

*Mounjaro®/ Tirzepatide is part of another similar class of medications called dual GLP-1/GIP receptor agonists.

5 natural GLP-1 alternatives to consider according to science 

Alternatives to GLP-1 agonists have existed for centuries, rooted in traditional remedies and now supported by modern science. 

Whilst they may not deliver the rapid weight loss associated with drugs like Ozempic, many natural options have been clinically studied for their ability to support

• insulin action
• blood sugar balance
• appetite control
• metabolic health 

These GLP-1 alternatives offer a sustainable, holistic approach to blood sugar control and metabolic health. Below is Avea’s list of the top 5 natural ingredients, each backed by clinical research. What’s more, some of these ingredients may work in synergy, amplifying each other’s benefits for even greater results.

1. Berberine

A polyphenol with over 2500 years in Ayurvedic and Chinese medicine. Proven in clinical studies to deliver effects similar to Metformin (the first-line prescription for treating diabetes), Berberine significantly reduces HbA1c levels*, enhances insulin sensitivity, and decreases glucose production in the liver. 

It also supports fat metabolism, helping to lower visceral fat and improve body composition—all without the side effects typically associated with other prescription drugs. It’s being called ‘’nature’s Ozempic’’ for a fair reason.

At high dosages, Berberine can react with certain medications and cause mild side effects like gastrointestinal discomfort.

*HbA1c levels is a marker for glucose management.

2. White Mulberry Leaf: Reducose®

White Mulberry Leaf extract, known as Reducose®, has been a staple in traditional Asian medicine for centuries and is now acclaimed for its ability to regulate glucose spikes and support metabolic health. Reducose® works by slowing the conversion of carbohydrates into glucose, reducing post-meal blood sugar and insulin levels by up to 40%. 

This encourages your body to use fats more effectively for energy, supporting weight management. Besides, lower insulin levels benefit cognitive function, while undigested carbs act as prebiotics, promoting gut health.

Clinical studies have shown that Reducose® does not cause any unwanted gastrointestinal side effects.

3. Magnesium 

Magnesium is a mineral involved in over 300 biochemical reactions, making it essential for metabolic health. It supports glucose metabolism by improving insulin sensitivity and promoting better glucose uptake. 

Magnesium also helps reduce inflammation, a common disruptor of insulin signalling, and supports muscle function—key for weight management. High doses may cause mild digestive discomfort, like diarrhoea.

4. Caffeine

Caffeine, a natural stimulant found in coffee beans, tea leaves, and cacao pods, is known for its ability to energise and enhance metabolism. It promotes fat oxidation, supports thermogenesis, and may aid modestly in weight loss and weight maintenance[2]. 

Its metabolic-boosting effects make it a potential complement for regulating glucose and managing appetite. However, excessive consumption can lead to insomnia, jitters, or an increased heart rate, so moderation is key to reaping its benefits without side effects.

5. Chromium Picolinate

Chromium Picolinate is the most bioavailable form of chromium, making it a vital component of metabolic health. 

As an essential trace mineral, chromium enhances insulin sensitivity by supporting insulin receptor activity, allowing cells to absorb glucose more effectively. 

Research highlights its ability to stabilise blood sugar levels and curb cravings. It also reduces oxidative stress and inflammation, whilst promoting fat metabolism. Mild side effects like headaches or sleep disturbances are rare when taken at the recommended doses.

Synergy of ingredients for blood sugar control

Certain natural ingredients don’t just work well independently—they can amplify each other’s effects when combined. 

For instance, Berberine is great at lowering fasting glucose levels by regulating liver glucose production, whilst Reducose® targets post-meal glucose spikes by inhibiting carbohydrate absorption. Chromium complements these actions by enhancing insulin sensitivity, facilitating more effective glucose uptake into cells. 

Together, these mechanisms create a synergistic effect, offering a comprehensive solution for blood sugar control and metabolic health. 

This is why Avea developed the Stabiliser—a revolutionary natural blood sugar stabilising formula that blocks the absorption of carbs by up to 40% while you eat. Here’s the real kicker: it helps you avoid blood sugar spikes and crashes whilst still allowing you to enjoy the foods you love.

Avea’s Stabiliser

Our Stabiliser is a groundbreaking supplement that combines clinically proven ingredients—Berberine, Reducose®, and Chromium Picolinate.

What sets this supplement apart? 

The Stabiliser can block an average of 40% of carbohydrate absorption during digestion, preventing the dreaded post-meal sugar crash.

Its effects are both science-backed and measurable in real time through CGMs, allowing you to see flattened glucose curves and reduced spikes immediately after meals. 

Whilst GLP-1 agonists focus on one specific pathway, ingredients in the Stabiliser work in synergy to address multiple mechanisms within your body to boost your metabolic health. 

How can the Stabiliser help with weight management?

Real-time control: Lower glucose spikes by 40%

• Reduced cravings
• Increased energy levels
• Weight management support
• Improved blood sugar levels

BUY NOW

Avea Stabiliser

The Stabiliser can provide weight management through multiple mechanisms:

1. Enhancing glucose metabolism

Berberine: Activates AMPK to improve glucose uptake and insulin sensitivity.

Reducose®: Slows carbohydrate breakdown, stabilising post-meal blood sugar.

Chromium Picolinate: Boosts insulin efficiency for balanced blood sugar and reduced insulin resistance.

2. Promoting fat utilisation

Berberine activates AMPK, shifting metabolism from fat storage to fat burning, aiding weight loss.

3. Reducing carb absorption

Reducose® moderates glucose release, preventing sharp blood sugar spikes and insulin surges.

4. Curbing appetite and cravings

Chromium Picolinate helps regulate appetite and reduce sugar cravings, supporting healthier eating.

Health benefits from the Stabiliser

• Reduced cravings: Experience a noticeable decrease in hunger and cravings, especially after carbohydrate-rich meals.
• Enhanced energy levels: Feel more energetic throughout the day, avoiding the typical post-meal fatigue associated with blood sugar spikes.
• Improved blood sugar stability: Benefit from more stable blood sugar levels, leading to fewer fluctuations and a balanced mood.
• Better appetite control: Experience reduced hunger, helping in portion control and healthier eating habits.

A 3-in-1 solution to support your goals

The Stabiliser could be the ultimate 3-in-1 solution as a natural GLP-1 alternative, combining blood sugar regulation, appetite control, and sustained energy support in one formula. It’s designed to target multiple pathways for optimal metabolic health.

Real-time control: Lower glucose spikes by 40%

• Reduced cravings
• Increased energy levels
• Weight management support
• Improved blood sugar levels

BUY NOW

Avea Stabiliser

Here are 5 reasons why you should consider it:

1. Budget-friendly

GLP-1 agonists can cost over €950 per month, making them inaccessible for many. Avea’s Stabiliser offers an affordable, effective solution for managing blood sugar and weight without breaking the bank.

2. Boosts longevity

Blood sugar imbalances affect more than just those with diabetes. According to the Glucose Goddess, over 90% of people unknowingly carry excess glucose, leading to fatigue, brain fog, and metabolic issues. The Stabiliser improves insulin sensitivity, stabilises blood sugar, and activates longevity pathways, reducing inflammation and supporting cardiovascular and brain health.

3. Convenient and accessible

GLP-1 agonists require invasive injections. The Stabiliser is a simple daily capsule taken before heavy meals, fitting seamlessly into your routine.

4. Safe and effective

Natural, clinically tested ingredients make the Stabiliser a safe alternative to GLP-1 agonists, delivering results with minimal side effects.

5. Enjoy the foods you love

It’s impossible to always eat perfectly—whether you’re a guest, a host, at a business dinner, or enjoying a cheat day. But staying smart is always an option. The Stabiliser can be your go-to supplement no matter the occasion.

Customer reviews

‘’Super product. I am no longer craving after carbohydrate-rich meals, which used to be the case after 2–3 hours. Absolutely recommendable!’’ –Kristina, June 2023.

Internal study results

“For those who wear a glucose monitor, the difference is clear: flatter glucose curves and reduced spikes. It’s perfect for when healthy food isn’t an option—business dinners, hosting guests, or just enjoying a treat without worry.” – Adriana M., August 2023.

Here are some of the immediate blood-glucose stabilising effects on various meals, obtained in our internal study done with a CGM.

Note: The Stabiliser is not intended to treat or manage diabetes. If you have a medical condition, such as diabetes, or are on any medications, consult your doctor before introducing any supplement into your routine.