‘’All round changes were noticeable–improved hydration and elasticity, a more even skin tone, as well as reduced fine lines. I was surprised at how quickly I saw the changes.’’
Meet Isabel–a wellness professional who has built a life around her passion for the mind-body connection.
She specialises in using a holistic mind-body-soul approach to help men achieve balance through behavioural change, better sleep, and reduced anxiety.
With a genuine desire to uplift those she supports, Isabel is committed to testing and sharing effective products that can improve both physical and mental health.
This drive led her to a pivotal opportunity: participating in Avea’s 6-month clinical study to explore the benefits of our Collagen Activator.
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The experiment
‘’I found the study to be professionally organised, and the instructions were practical and clear. I enjoyed being a participant, and I’m grateful to get all the results afterwards too. Thank you Avea!’’
Avea embarked on a mission many of you have been waiting for: to evaluate the power of our Collagen Activator. Our focus?
- Skin health enhancement: As a collagen-boosting supplement, we wanted to see its effect on skin hydration, elasticity, and texture.
- Biological age impact: We also measured changes at the cellular level, assessing how our longevity supplement can affect internal ageing markers.
The importance of collagen
Collagen is the most abundant protein (about 30% of your body’s total protein content), providing structural integrity to your skin, bones, muscles, and connective tissues.
But as you hit your 20s, collagen synthesis declines by roughly 1-2% each year. This eventually leads to the visible signs of ageing, such as wrinkles and sagging skin, and a decrease in joint flexibility. It’s likely that 50% of your collagen will be depleted by in your 60s.
To make matters worse, collagen loss is also triggered by:
- smoking
- alcohol consumption
- high sugar intake
- UV exposure
- lack of sleep
- lack of physical activity
- unresolved stress
- micronutrient deficiencies
- poor protein digestion
Why we created the Collagen Activator
Avea’s Collagen Activator aims to counteract this decline by stimulating optimal endogenous collagen production in your body. Meaning, our formula is designed to enhance your body’s natural ability to produce collagen efficiently.
It is developed in collaboration with ETH Zurich scientists, who have helped us ensure our formulation is backed by rigorous testing and scientific research. Learn more about the science behind the Collagen Activator.
With over 10,000 satisfied customers, we aimed to push the science even further. Our goal was to explore how the carefully chosen ingredients in our formula could maximise your body’s ability to sustain collagen production, keeping your skin and body healthier as you age.
The hypothesis was that the Collagen Activator can boost skin health in several ways. By increasing collagen production, it can activate fibroblasts, which strengthen the skin and improve moisture retention, making the dermis thicker and better at holding water.
Collagen peptides can also enhance the skin barrier, reducing water loss and locking in hydration for a plump, smooth appearance. Additionally, they provide antioxidant protection, preventing skin damage and dryness.
To test this, we had to measure the following:
| Parameters | Method used |
| Skin hydration | Corneometer |
| Elasticity | Cutometer |
| Thickness & density | Ultrasound Dermascan |
| Wrinkles & texture | Visia analysis |
This led to another collaboration with leading dermatology experts at Hautwerk Clinic in Zurich. With a clinical trial enrolling 58 participants, we set out to validate the efficacy of our ingredients and dosage in the Collagen Activator.
And just a heads-up—research conducted at ETH Zurich had already demonstrated that our ingredient blend is not only 4x more effective than regular collagen supplements, but could also extend lifespan in model organisms.
Inspired by these promising findings, we aimed to understand how this translates to human health. That’s why a biological age test was used both in the beginning and at the end of the experiment.
Your biological age reflects how well your cells and tissues are functioning compared to your chronological age. By focusing on biological age, we can better assess the potential of our formula to promote longevity and cellular vitality.
Are you ready? Let’s discover Isabel’s story.
The methodology
Isabel’s 6-month journey with Avea’s Collagen Activator was part of a well-structured study involving over 58 healthy adults.
The participants, including Isabel, had to meet strict criteria:
- Aged 35 and above
- No prior use of collagen supplements
- No pre-existing skin conditions
- No chronic diseases
- No current medications
- Non-smokers
The intervention was simple yet consistent: a daily intake of one sachet of Avea’s Collagen Activator for six months.
 |  |  |
| Use one sachet of the Collagen Activator | Mix in 250 ml of cold water | Enjoy the refreshing taste (lemon or raspberry) |
‘’The sachets are individually wrapped so they were easy to use.’’
To assess the supplement’s impact, Avea went for a comprehensive approach:
- VISIA Skin Analysis: This non-invasive, state-of-the-art imaging system offered a detailed look at various skin parameters:
- Spots: Areas of surface discolouration, like freckles and hyperpigmentation.
- Wrinkles: Creases and lines linked to reduced elasticity.
- Texture: Smoothness and evenness of the skin surface.
- Pores: Visible sweat gland openings that affect overall complexion.
- UV spots: Sun damage not visible to the naked eye, indicating deeper damage.
- Brown spots: Hyperpigmentation both on and beneath the skin.
- Red areas: Regions with increased blood vessels or inflammation.
- Porphyrins: Bacterial excretions that can lead to acne.
- The VISIA Cam®: This used cross-polarised light and UV illumination to reveal both surface and deeper skin layers. The system’s algorithm compared Isabel’s skin to a database of individuals with similar age, gender, and skin type, providing reference values in percentages and mapping the condition visually.
- Biological age testing: TruMe Labs performed an epigenetic clock test using saliva samples to determine Isabel’s biological age. This measure provided insight into her cellular ageing, reflecting how well her body was functioning compared to her chronological age.
- Monthly questionnaires: Isabel had to complete detailed questionnaires each month, capturing self-reported changes in skin health, overall well-being, and any perceived benefits from the supplement.
By combining quantitative skin assessments, advanced biological age measurements, and qualitative feedback, our study offered a comprehensive view of the Collagen Activator’s impact on ageing and skin health, both inside and out.
The results
‘’After the first month, my skin already seemed more hydrated, and the small lines on my forehead reduced.”
Seeing clear improvements, Isabel felt motivated to continue till the end, confident that the changes would only get better.
Throughout the 6-month study, her experience with Avea’s Collagen Activator showed remarkable transformations, both in her personal observations and through measurable scientific assessments.
VISIA Skin Analysis highlights
Here’s the full summary of Isabel’s skin results after 3 months:
- Hydration: Her skin hydration, especially in her cheeks and arms, surged, reaching up to +18.6%.
- Spots: A remarkable +144.4% improvement, evening out her skin tone and significantly reducing hyperpigmentation.
- Wrinkles: An initial increase that eventually smoothed out to a -7.1% decrease, giving her a more youthful appearance.
- Texture: Improved rapidly by +73.9% within the first month, stabilising at +39.1%, leaving her skin polished and refined.
- UV spots: Reduced underlying sun damage, with a +42.9% improvement at one month, tapering to +14.3% at three months.
- Brown spots: A minor reduction, with -4.3% at one month and -2.2% at three months.
- Red areas: Lessened inflammation, improving by +11.8% in the first month and +4.4% by the end of three months.
- Porphyrins: Remained unchanged, likely indicating a stable and healthy skin microbiome.
The impressive results Isabel experienced are most rooted in the Collagen Activator’s ability to boost natural collagen production and beyond.
By providing amino acids like proline, glycine, and hydroxyproline, which are the primary amino acids of collagen, the Avea Collagen Activator supports collagen regeneration, enhancing skin hydration, elasticity, and evenness. These foundational building blocks allow the skin to repair and strengthen from within, visibly improving all key parameters over time.
Vitamin C also plays a crucial role in collagen synthesis, acting as a co-factor that stabilises and strengthens collagen fibres.
Astaxanthin, a potent antioxidant, protects skin cells from oxidative stress, preventing further breakdown of collagen and maintaining youthful skin.
Fun fact; Astaxanthin has incredible antioxidant power—up to 6,000x stronger than Vitamin C, and 100x more potent than Vitamin E.
Biological age: reversing time at the cellular level
‘’I was thrilled to see a significant improvement in my bio age after 6 months. The results spoke volumes.” .
The effects of the Collagen Activator went deeper than skin. Isabel’s biological age results were stunning, despite reducing her intake to 2–3 times a week in the final weeks:
- Baseline: 49.7 years (vs. her chronological age of 48.3 years).
- After 6 months: Reduced to 41.2 years, despite her chronological age increasing to 48.8 years.
Biological age, a more accurate health marker than chronological age, reflects how your lifestyle choices affect your ageing process overtime. Learn how to test your biological age.
The impressive 8.5-year reduction in her biological age validated her experience, highlighting the supplement’s significant impact on her overall sense of vitality and well-being.
This drop in bioage is likely due to the potency of ingredients like CaAKG, known for supporting cellular health and longevity. In a nutshell, it optimises metabolic processes and mitigates ageing at the DNA level by enhancing energy production and reducing cellular damage.
By lowering biological age, the Collagen Activator helps sustain youthfulness and may protect against age-related diseases, making it a powerful ally in long-term health and well-being.
‘’I will continue to use the Collagen Activator as I see the visible results, and I also feel good.”
Isabel has even started recommending Collagen Activator to her friends, convinced by both the skin benefits and the overall wellness impact.
Why is Avea’s Collagen Activator is worth it?
Isabel’s case suggests that regular use of Avea’s Collagen Activator could provide a holistic approach to healthier ageing, benefiting both skin appearance and internal markers of vitality. Dive deeper into the 12 hallmarks of ageing.
1. 100% vegan formula
Our Collagen Activator is animal-free; it uses collagen precursors designed for efficiency. Many collagen supplements rely on animal-derived peptides, but our vegan-friendly approach makes it accessible to everyone whilst still delivering exceptional results. It’s a true game-changer in the wellness world, supporting sustainability without sacrificing effectiveness.
2. Patent-pending Colgevity™ blend
Collaborating with ETH Zurich scientists allowed us to create a scientifically developed ratio of amino acids called Colgevity™. Instead of using whole collagen molecules—which are too large to be absorbed—we focus on highly bioavailable building blocks like proline, glycine, and hydroxyproline. These are directly used in the body to stimulate collagen turnover, making our blend 4x more effective than traditional collagen supplements.
3. Ingredients that work in synergy
Our formula integrates powerful co-factors with the collagen precursors. Vitamin C, known for its collagen-enhancing properties, pairs with Astaxanthin, a potent antioxidant that is 6,000x stronger than Vitamin C in neutralising free radicals. CaAKG doesn’t just support collagen but also optimises energy pathways, reducing cellular damage at the DNA level.
4. Benefits beyond skin health
The benefits of collagen go beyond making you look young. It plays a crucial role in maintaining joint, bone, and connective tissue health. Our synergistic ingredients amplify these effects, ensuring holistic support for your body as you age. With every dose, you’re not just nourishing your skin, but also enhancing your body’s structural integrity and cellular longevity.
5. Scientifically tested
Our Collagen Activator has undergone rigorous testing both on yeast, a well-used model organism, and in human trials. The results were consistently positive: yeast studies demonstrated promising effects on longevity, and human studies, like Isabel’s case, showed significant improvements in skin health and a reduction in biological age. This dual approach ensures our formula is backed by robust science whilst aligning with our commitment to vegan and ethical standards.
‘’The Collagen Activator continues to be a valuable addition to my self-care routine. It’s not just about looking good but feeling healthier, everyday’’.
General learnings from the Collagen Activator study
After 30 days,
- 67% of participants showed improved skin texture.
- 95% improvement in skin hydration.
- 97% of participants reported being happier with the quality of their skin.
- 64% of participants showed increased skin elasticity.
