As you age, maintaining healthy NAD+ levels becomes increasingly important if you want to stay energised and keep your immune system strong.
By increasing NAD+, you give your cells the energy and tools they need to stay healthy, repair damage, and reduce harmful processes linked to ageing.
While NMN supplementation lays the foundation for boosting NAD+ levels, research shows that a multitarget approach can further maximise its benefits.
Supporting NAD+ from every angle includes:
- Optimising how NAD+ is produced and used.
- Protecting NAD+ from depletion.
- Enhancing the recycling cycle of NAD+.
NMN supplements alone can only solve part of the problem. But when combined with scientifically researched ingredients involved in the key pathways mentioned above, NAD+ levels are best restored!
After digging deep into the science of NAD+ metabolism, Avea created the Vitality Bundle—an innovative duo combining NMN with the Booster.
The Avea Booster is a revolutionary blend of six potent antioxidants, each chosen to work in synergy with NMN to optimise NAD+ levels and promote better energy, repair, and overall health.
Discover why NMN works best when paired with our NAD+ Booster—and how this duo deserves its place in your longevity routine.
In this article
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What is NAD+?
NAD is one of the most ubiquitous molecules in your body. It is involved in over 600 biological pathways. Found in all living cells, it helps with energy production, DNA repair, and gene regulation.
As a co-factor, NAD is not consumed in a chemical reaction, but rather serves as an electron shuffle.
NAD+ and NADH are like a team, passing energy back and forth to power your cells. NAD+ helps create energy, while NADH carries it to where it’s needed most.
They basically play catch with electrons, and that’s what NAD is doing 99% of the time in your body.
NAD levels are tightly controlled in your body, just like blood sugar, pH levels, or hydrogen ion concentrations.
For instance, our body’s pH must stay within a very narrow range—between 7 and 7.8 on a 0-14 scale—for survival. If it goes outside this range, even slightly, we simply die.
Similarly, NAD is carefully regulated to keep our cells functioning properly in all stages of life and under all conditions.
NAD+ levels decrease with age
As we age, two major problems arise:
- We produce less NAD+ as natural pathways like the salvage pathway slow down.
- We lose NAD+ faster because enzymes like CD38 and stressors deplete it.
How can you increase your NAD+ levels?
If you only focus on boosting NAD+ through NMN (a direct precursor), you’re addressing just one piece of the puzzle. The real challenge is to ensure the entire system works seamlessly together.
To make sure your body uses NAD+ effectively, we need to address a few things (see the visual graphic for reference):
- Stop NAD+ from being used up too quickly: Some enzymes, like CD38 and PARPs, act like NAD+ drains—they use up too much of it. By blocking these enzymes and reducing DNA damage (which activates PARPs), we can save NAD+ for more vital tasks.
- Boost NAD+ recycling: Your body has a system (called the Salvage pathway) that recycles NAD+, like a renewable energy system. An enzyme called NAMPT is key to this process. By activating it, we can help the body make more NAD+ from the materials it already has.
- Reduce NAD+ waste: Sometimes, the body diverts NAD+ into waste through an enzyme called NNMT. If we can block NNMT, we’ll prevent unnecessary NAD+ loss and ensure more is available for vital functions.
In short, it’s about saving NAD+, recycling it efficiently, and cutting down on waste—like managing money wisely to get the most out of it.
The NAD+ Booster for optimal benefits
Countless hours of research led to the development of a breakthrough solution to optimise how NAD+ is produced, utilised, preserved, and recycled in the body.
We call it the Vitality Bundle– a duo of NMN and the Booster.
Avea designed the Booster to perfectly complement our NMN supplement to boost and maintain optimal levels of NAD+ daily.
It contains ideal dosages of 6 potent antioxidants, combined with olive oil for maximal absorption.
How does the NAD+ Booster work?
1. Recycling NAD+ efficiently
Your body has a natural system called the NAD+ salvage pathway, which helps recycle NAD+ instead of letting it go to waste. This process ensures your body can maintain a steady supply of NAD+ for essential functions like energy production and repair.
Like any well-functioning recycling system, the salvage pathway relies on enough raw materials, minimal waste build-up, and optimised NAD+ usage.
The Booster supports the NAD+ salvage pathway as follows:
- Nicotinamide (NAM): Provides the raw material required to restart the salvage pathway, ensuring a consistent supply of NAD+ for energy and repair.
- Betaine: Acts as a methyl donor to prevent excess Nicotinamide from clogging the system, keeping the recycling process smooth and efficient.
- Resveratrol and Pterostilbene: Activate sirtuins, longevity enzymes that improve NAD+ recycling and direct it to essential functions like DNA repair and inflammation control.
By addressing each part of the recycling process, the Booster ensures steady NAD+ production and supports optimal cellular health when taken with the NMN.
2. Protecting and preserving NAD+
As you age, NAD+ levels drop—not only because your body produces less, but also because it’s depleted more quickly by enzymes and stress.
For instance, CD38 is an enzyme that becomes overactive with age, consuming NAD+ unnecessarily. Oxidative stress also damages your cells and uses up NAD+ during repair.
The Booster aims to preserve NAD+ as follows:
- Apigenin: Slows down CD38’s activity, helping preserve NAD+ for important functions like energy production and repair.
- Pterostilbene: Protects your cells from oxidative damage and reduces inflammation, which helps conserve NAD+ and reduces unnecessary consumption.
While NMN boosts your NAD+ levels, ingredients in the Booster essentially help in maintaining healthy NAD+ levels, ensuring they are available for where they are needed the most.
3. Enhancing mitochondrial efficiency
Mitochondria produce the energy your body needs, but as they age, they become less efficient, consuming more NAD+ and generating harmful by-products.
The Booster includes CoQ10 (Ubiquinol), which:
- Improves how mitochondria produce energy, ensuring they function more efficiently.
- Reduces damage caused by harmful by-products, preserving NAD+ for other critical functions.
While NMN gives your cells the energy base they need to function, by supporting mitochondrial health, the Booster ensures your body maintains its energy levels and NAD+ reserves for long-term health.
The Avea Vitality Bundle works to boost, recycle, protect, and optimise NAD+, giving your body everything it needs to stay energised, resilient, and performing at its best every day.
NMN and the Booster are two halves of a complete solution. Together, they tackle every angle of NAD+ metabolism, ensuring you get the most out of your supplement routine
Top 5 benefits of taking NMN with NAD+ Booster
Here’s what you can expect when you optimise your NAD+ metabolism with Avea’s Vitality Bundle:
- More sustained energy throughout the day: Tackle your daily routines easily and stay on top of your goals.
- Better recovery after exercise: Bounce back faster from workouts or physical activity.
- Stay sharp and focused: Get more done with clearer thinking and better concentration throughout the day.
- Better sleep quality: Support your body’s natural sleep-wake cycle and wake up feeling more energised and refreshed.
- A stronger foundation for long-term health: Build a resilient body that supports your lifestyle and future goals.
Customer study results: The impact of the Vitality Bundle
 |  |  |
| Energy & Focus | Overall Wellbeing | Mood & Emotional Wellbeing |
| 88.5% report more energy and focus in 3 months | 77% report improved overall wellbeing in 30 days | 77% report improved mood and emotional wellbeing in 30 days |
Customer reviews
FAQs
1. How long does it take to feel the effects?
Most users notice improved energy and focus within the first few weeks of consistent use. Recovery, sleep quality, and other long-term benefits may take a few months as your NAD+ levels stabilise and your body adapts.
2. Can I take the Booster without NMN?
Yes, the Booster is effective on its own, as it supports NAD+ recycling, protection, and optimisation. However, pairing it with NMN provides a comprehensive solution, boosting NAD+ levels while enhancing how it’s used and preserved.
3. Are there any side effects?
The Vitality Bundle contains natural and well-researched ingredients and is generally well-tolerated. As with any supplement, we recommend consulting your healthcare provider, if you have any pre-existing conditions or are taking medications.
4. What makes the Vitality Bundle different from other NAD+ supplements?
Unlike single-target NAD+ supplements, the Vitality Bundle combines NMN with the Booster to address every aspect of NAD+ metabolism:
- Boosting production with NMN.
- Recycling and protecting NAD+ with scientifically researched ingredients.
This multitarget approach ensures better results, making it a complete solution for improving energy, repair, and resilience.
5. What happens if I stop taking the Vitality Bundle?
Sophie, one of the founders and scientists behind Avea formulations, did an exciting experiment to validate the efficacy of our products. Read her case study and find out what happened when she stopped taking the Vitality Bundle.
